• Thursday , 16 August 2018

Flagyl (Metronidazole)

Flagyl (Metronidazole) Dr H. Scheele
Drug Review



Generic Name: Metronidazole
Brand Names: Flagyl ER
Dosage: 200mg, 400mg
Generic Flagyl is a pharmaceutical that is used in gynecological practice as a drug for local administration. The mechanism of its action comes from the capacity of inducing 5-nitroimidazolebiochemical restoration. It is done for account of intracellular transport proteins that basically belong to anaerobic and elementary organisms. It results in microorganism’s cell inhibiting amino acids and destructing it, consequently.

Flagylis also known by the name of its active material, which is metronidazole. This pharmaceutical is notable for being listed by World Health Organization as one of the safest and most effective medications required in healthcare system.

There are many online drugstores that offer their customers to buy Flagylonline without a prescription. Although there could be quite attractive offers, it is important to think twice before taking the drug on your own. Always consider a consultation with your physician first.

Remember that the following guidelines about generic metronidazoleare given for introductory purposes only. This information should not substitute for medical advice!

Important information and precautions

Medics warn people against drinking alcohol while taking generic Flagyl. Such improvidence increases the probability of adverse reactions development (tachyrhythmia, fever feeling, vomiting, etc.).

The prolonged period of treatment requires strict control over haematological characteristic. Patients who suffer leukocytopenia development often face the choice of whether or not they should take Flagyl in what follows. Typically, the answer comes from the risk of infection process onset.

Women who undergo a course of trichomonal vaginitis treatment with Flagyl need to avoid having sex during the therapy. The treatment should not be discontinued during the menstruation.

Evident neurologic symptomatology indicates that it is necessary to discontinue taking Flagyl.

Metronidazoleis known for its capacity of treponemes immobilization. As experience has shown, this effect might lead to false-positive Nelson’s reaction.

Pharmacological effect of Flagyl

Metronidazole is considered to be one of nitroimidazoles. The interaction of Flagyl with microbe’s DNA shows how efficient it is: consequently, this disease-producing germ loses its ability to propagate. That is why Flagyl is known as a quite effective pharmaceutical, which action it characterized by a broad spectrum. Particular efficiency of this medicine is ovserved when the active material interacts with the following causative agents:

  • Entamoebahistolytica
  • Peptostreptococcus spp.
  • Fusobacterium spp.
  • Bacteroides spp.
  • Giardia intestinalis
  • Clostridium spp.

Facultative anaerobesare proven to have no susceptibility towards metronidazole.

Uses of generic Flagyl

Doctors typically prescribe Flagyl for patients who suffer:

  1. Abdominal cavity infectious diseases: hepatic abscess, peritonitis.
  2. Small pelvis organs infectious diseases: ovary abscess, endometritis, Fallopian tubes abscess.
  3. Protozoan infectious diseases: amebic hepatic abscess, leishmaniasis, trichomoniasis, lambliosis, balantidiasis, mycotic urethritis, vaginitis, intestinal and extraintestinalamoebiasis.
  4. Infectious diseases of CNS: brain abscess, meningitis, septicaemia, empyema, bacterial endocarditis.

In addition, Flagylmight be prescribedto facilitate the prophylaxis of postoperative complications after colon, pararectal area, and gynecological surgeries.

What are the adverse reactions to Flagyl without a prescription?

The following negative effects might develop during the course of treatment with Flagyl:

  • Nervous system: coordination disturbance, mental confusion, sleeplessness, increased irritability, giddiness, depression.
  • Allergic reactions: face hyperemia, nettle rash, fever, allergic rhinitis.
  • Gastrointestinal tract: stomatitis, diarrhea, pancreatitis, nausea, epigastrium pains, vomiting, anorexia.

If you want to prevent the mentioned adverse reactions, it is necessary to use Flagyl only with a physician’s prescription.

What should I do in case of overdose with Flagyl?

The administration of 12 mg of metronidazole has shown the development of vomiting, ataxia, and mild disorientation. If you have noticed any concerning signs of overdose, seek for emergency medical aid as soon as possible.

The specific antidote is unknown. A case of overdose requires standard measures that are recommended when intoxicating with pharmaceuticals: gastric lavage, activated carbon administration, and symptomatic therapy.

What if I missed a dose of Flagyl?

You can just take it whenever you have remembered, unless the next scheduled dose is near.

How to buy metronidazole online legally?

Quite a number of online pharmacies offer Flagyl for sale. First, you should make sure that it is allowed to purchase Flagyl without a prescription in your country or state. You can do that by checking your local law.

Such online pharmacies provide their customers with a simple procedure of order placement: you would need to add your item to cart, select a payment method (for example, PayPal), and proceed with your order. Be sure to buy only at drugstores that have a good customer feedback.