• Saturday , 19 August 2017

Levitra (Vardenafil)

Levitra (Vardenafil) Dr H. Scheele
Drug Review

Summary:

4.1

Generic Name: Vardenafil
Brand Names: Levitra, Staxyn
Dosage: 10mg, 20mg
As of today, generic Levitra presents itself as a potent cure that treats various forms of male erectile dysfunction and has prolonged action time. This medicine is also known as vardenafil, due to the name of its active material. The latter is a special component of phosphodiesterase 5 group. Apart from the prolonged duration (35 hours and longer), its distinctive characteristic reveals itself in selective action that is performed only towards penis unstriped muscles. Levitra is responsible for intensification of blood flow and filling cavernous bodies with blood. These processes are the basis of natural erection.

Some people may consider the following aspects as important ones: generic vardenafil is not a hormonal preparation and it does not influence the state of mind. Thus, Levitra:

  1. Intensifies selectively the blood flow to cavernous bodies of penis
  2. Obstructs the derivation of blood
  3. Facilitates the natural and healthy erection for prolonged term

It is important to understand that cheap Levitra is not the medication that causes sexual arousal. Instead, it guarantees 100% natural erection when you experience really intense sexual desire.

Pharmacological action of generic Levitra

The active component, which is vardenafil, is responsible for the selective inhibition of phosphodiesterase 5. The latter is important due to at least one significant function: it is a part of physiological mechanism of erection itself. Such inhibition leads to:

  1. Increase in level of cyclical guanosine monophosphate
  2. Relaxation of smooth muscle vessel layer
  3. Increased blood flow to penis tissues

The effect of Levitra develops only in case of sexual stimulation. The latter implies that nerve endings of cavernous bodies release nitric oxide that starts up the reaction of cyclical guanosine monophosphate level increasing.

Due to the high selectivity of vardenafil as regards phosphodiesterase 5, Levitra has no influence on organs and systems which functions are regulated by other phosphodiesterases.

Safety precautions

There are some categories of people that should avoid using generic Levitra:

  • Anyone who has the susceptibility towards vardenafil
  • Children
  • Women

Medical surveillance and carefulness are required when a patient has:

  • Acute renal disease
  • Liver dysfunction
  • Penis deformation
  • Priapism tendency
  • Inherited retina disease
  • Angina pectoris
  • Exacerbated ulcer

When a patient is renewing his health after the illnesses like myocardial infarction or stroke, there is some risk in respect of taking Levitra.

How am I supposed to use generic Levitra without prescription?

Generic vardenafil is supposed to be swallowed up entirely with enough amount of water. As a rule, people take it independently from ingestion 30-60 minutes before the sexual activity. Taking into consideration the approximate duration of Levitra, doctors find it conceivable to take the drug 4-6 hours before expected sexual activity. Keep in mind that the development of desirable effect requires the sexual stimulation.

The dosage of Levitra is usually determined by physician. In most cases, the initial dose would be 10 mg, although it might be increased to 20 mg or decreased to 5 mg according to the medicine’s efficiency and tolerance.

There is a recommendation to avoid using Levitra more than once per day.

The initial dose of 5 mg is usually recommended for elderly patients and those who suffer the diminished renal function.

Possible adverse reactions to Levitra

In most cases, people tolerate Levitra quite well. There have been rare cases of negative effect development among patients. Clinical and post-marketing studies have mentioned the following side reactions of this pharmaceutical:

  • Respiratory apparatus: swollen Schneiderian membrane, rhinorrhea
  • Vessels: arterial pressure lability, cardiac muscle ishaemia, heart stroke, vasodilatation
  • Nervous system: increased fatigability, somnolence, giddiness, sleep disorder, spasms, paresthesia
  • Other: increased muscle tone, low-back pains

Do not wait until any of the effects will become stronger; consult your MD in case you have noticed any of them.

Is it possible to overdose with Levitra without prescription?

As experience has shown, the dosage schedule like 80 mg per day and 40 mg per day during a month caused no severe side reactions. That being said, when using 40 mg twice per day, you may expect apparent low-back pains. The symptoms of toxic influence would be absent.

This case needs supporting and symptomatic treatment; hemodialysis would hardly be efficient.

How does Levitra interact with other pharmaceuticals?

The simultaneous taking of the drug with nitrates and other NO donators is prohibited. The combination with preparations that inhibit or induce the ferments of cytochrome P450 might change the disposition profile of the medication. In particular, there is a possibility of increased plasma concentration of the active material if taking at the same time with:

  • Indinavir
  • Ritonavir
  • Ketoconazol
  • Erythromycin

Levitra should be prescribed with caution if a patient gets alpha-adrenergic blocking agents.

How to buy Levitra online legally without prescription?

A variety of online pharmacies offers their customers the opportunity to buy vardenafil online just by placing an order. It allows you to get an overnight delivery of Levitra for sale.

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