• Thursday , 16 August 2018

Valium (Diazepam)

Valium (Diazepam) Dr H. Scheele
Drug Review



Generic Name: Diazepam
Brand Names: Valium
Dosage: 10mg
Valium is a proprietary name for diazepam, which is a preparation that relieves people from anxious symptoms. It is notable for the reduction of nervousness and feeling of anxiety, as well as for general anxiolytic action. It is also characterized by pronounced hypnosedative, anticonvulsive, and neuromuscular relaxant actions.

Such influence of generic Valium on human body is conditioned by its capacity of potentiating the gamma aminobutyric acid’s central action, which is considered to be the main inhibitory transmitter of CNS.

Nowadays there are many online pharmacies where you can find cheap Valium for sale and get the overnight delivery. Nevertheless, be careful not to buy counterfeit product. Always place your orders only in online drugstores with an excellent reputation.

Uses of Valium

Doctors prescribe Valium when there is a need of single-drug therapy or multimodality therapy. First of all, it concerns patients who suffer:

  • Organic diseases of central nervous system
  • Dysphoria
  • Psychoses
  • Neuroticism

 It I also prescribed for those who have insomnia and cannot sleep. Valium may be taken in combination with other preparations to treat people with alcohol abstinency syndrome.

Contraindications to Valium

If somebody has individual intolerance towards the active material of tablets, diazepam should not be prescribed and/or taken.

It is also prohibited for patients with:

  • Hypercarbia
  • Suicide tendency
  • Porphyria
  • Myasthenia
  • Closed-angle (angle-closure) glaucoma
  • Drug dependence
  • Hepatitis
  • Alcohol addiction
  • Epilepsy or epileptic seizures in past history
  • Spinal or cerebral ataxia

The caution is highly required when prescribing this medication to patients who suffer renal or hepatic dysfunctions.

Speaking about pediatric aspect, Valium could be used only in treatment of kids aged 3 and older.

Doctors say that it is vital to stay away from potentially dangerous activities that call for an increased attention when taking this drug.

How should I take Valium?

Diazepam is meant for perioral administration. These tablets need to be taken irrespective of ingestion with enough amount of drinking water. Physician should determine the duration of therapy and dose of Valium for each patient individually.

Pharmacological action of generic Valium

Making selective inhibitory effect on specific regions of the cerebrum, diazepam:

  1. Leads to emotional and vegetative relaxation
  2. Settles one’s nerves
  3. Eliminates anxiety and uneasiness
  4. Improves the quality of sleep

The introduction of doses, which inhibit the spinal reflexes and influence specific structures of the cerebrum, makes it possible to achieve more evident relaxation of transversal muscles.

Valium absorbs quickly and completely in alimentary canal. The maximum concentration of the active material in blood plasma is reached in 30-90 minutes after the administration. After intramuscular injection, the absorption comes also as complete, although it may not always be quicker than after the perioral administration.

Generic diazepam facilitates the increase of neural tissue steadiness under conditions of oxygen starvation. It also increases the threshold of pain sensitivity, inhibits sympathoadrenal and parasympathetic paroxysms.

It is typical that when taking Valium patients observe the reduction of emotional tension, fear, anxious and uneasy feelings. In rare cases there is the abatement of affective tension.

Characteristically, this pharmaceutical has dose-dependent action on central nervous system:

  1. Lower doses (from 2 to 15 mg per day) have stimulatory action
  2. Higher doses (more than 15 mg per day) have anxiolytic action

Speaking about patients who have alcohol abstinence syndrome, Valium leads to the lessening of tremor, acute agitation, negativism, acute delirium alcoholicum, and hallucinations.

What should I do in case of overdose with Valium without prescription?

The overdose with Valium causes a number of symptoms:

  • Paradoxical excitation
  • Cardiac activity depression
  • Respiratory activity depression
  • Areflexia
  • Apneustic breath
  • Coma

If you are concerned with any signs like the abovementioned, it is very important to seek for emergency medical aid. Remember that it is your health and you should treat it with all the responsibility.

Adverse reactions to Valium

Usually, patients undergo a course of treatment with diazepam quite well. Nevertheless, the period of therapy may include the development of undesirable effects, such as:

  • Nervous system: sleep and memory abnormalities, mogiarthria, intense excitement, hallucination, giddiness, tremor, headaches
  • Allergic reactions: nettle rash, skin eruption
  • Alimentary and hepatobiliary system: stool abnormalities, jaundice, hypersalivation, increased activity of alkaline phosphatase and hepatic transaminases, nausea, dry tunica mucosa of mouth
  • Others: increased or decreased libido, involuntary urination

Valium may cause the development of drug dependence and withdrawal syndrome.

How to buy Valium online without prescription

If you have decided to buy diazepam online, it is important to go to the respectable pharmacies. Do a little research and learn what other people think about the chosen drugstore.

Keep in mind that if you want to purchase Valium legally, you need to check your local law.

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